Studies on Chemotherapeutics for Dermatomycoses. IV

Antifungal chemotherapeutics.

This review addresses trends in outcome and risk factors for invasive fungal infections, current antifungal agents and new therapeutic strategies. Current prospects for new therapies rest upon caspofungin, the first of a new class of antifungal molecules, the echinocandins, and new extended-spectrum azoles, voriconazole, posaconazole and ravuconazole. Approval by the Food and Drug Administratio...

Clotrimazole in treatment of dermatomycoses and vaginitis.

62 patients with dermatomycoses and 39 patients suffering from vaginitis were treated with topical application (1 X ) of clotrimazole (Canesten) cream and vaginal tablets (100 mg) respectively. A majority of the patients (44) of dermatophytoses were completely cured in 3 to 6 weeks and all cases (11) of cutaneous candidiasis in 1 to 2 weeks. 14 cases of candida vaginitis were cured in 2 weeks a...

Studies on Self-Sterility. IV. Selective Fertilization.

INTRODUCTION .................................................................. 346 Discussion of the problem ..................................................... 348 Pollen-tube frequency distributions ............................................. 349 Influence of growth of compatible pollen tubes upon incompatible pollen tubes.. .. 352 SUMMARY AND DISCUSSION ....................................

Structural studies on human type IV collagen.

Type IV collagen was isolated from limited pepsin digests of human placenta by selective salt precipitation at acidic and neutral pH. The native protein was resistant to human skin collagenase but was cleaved by a rat mast cell protease. Molecular sieve chromatography of the reduced and alkylated material separated relatively homogeneous components of molecular weight 140,000 (140K) and 100,000...

Studies on Plasma Protein. IV. Leprosy